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Breathing

Oxygenation index and oxygen saturation index

How much ventilator support a baby needs for their oxygen level: the oxygenation index (with an arterial PaO2) and the oxygen saturation index (with SpO2, when there is no arterial gas).

For education. Check against your unit's guidance and a second clinician before use.

cmH2O

Arterial sample, for the oxygenation index.

Preductal, for the oxygen saturation index.

%

Enter the mean airway pressure, FiO2, and a PaO2 or SpO2.

How this is calculated

  • OI = mean airway pressure (cmH2O) × FiO2 (%) ÷ PaO2 (mmHg). PaO2 in kPa is converted to mmHg (× 7.5).
  • OSI = mean airway pressure (cmH2O) × FiO2 (%) ÷ SpO2 (%).

Sources

Checked by NICUlearn, 6 Oct 2026.

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