Guideline
International guidelines regarding the role of IVIG in the management of Rh- and ABO-mediated haemolytic disease of the newborn.
International Collaboration for Transfusion Medicine Guidelines (ICTMG)2022Full text
- Anaemia and transfusion
- Jaundice and haematology
- Jaundice and phototherapy
- Medical
Summary
International evidence-based guideline from a convened expert panel on the use of intravenous immunoglobulin (IVIG) in neonates with Rh- or ABO-mediated haemolytic disease of the newborn. It considers whether IVIG reduces the need for exchange transfusion, bilirubin levels, red cell transfusion, anaemia severity, hospital stay and neurocognitive harm. The panel concludes IVIG should not be used routinely, with its role unclear where hyperbilirubinaemia is severe or exchange transfusion is unavailable. It highlights the need for high-quality research.
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- Open (Creative Commons)
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