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Guideline

ISNS General Guidelines for Neonatal Bloodspot Screening 2025.

International Society for Neonatal Screening (ISNS)2025Full text
  • Allied health
  • Cardiovascular
  • Congenital heart disease
  • Inborn errors of metabolism
  • Medical
  • Metabolic, endocrine and renal
  • Nursing
  • Postnatal and transitional care
  • Quality improvement

Summary

The International Society for Neonatal Screening presents its renewed 2025 general guidelines for neonatal bloodspot screening, focused on congenital biochemical disorders rather than cardiac or hearing screening. It offers a framework for screening programmes to develop policies across all aspects of the newborn screening system. The guidance serves as a checklist of minimum provisions for starting, expanding or maintaining well-organised programmes and for evaluating and improving their essential elements. It is intended as a starting point for ongoing discussion and refinement.

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