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Can symptom-based dosing cut hospitalization time for babies w neonatal opioid withdrawal syndrome?

The Incubator Channel · 25 May 2026 · 23 min

Summary

Ben and Daphna review the Optimized NOW multicentre randomised trial in JAMA, which compared symptom-based opioid dosing with a scheduled opioid taper in infants with neonatal opioid withdrawal syndrome managed with Eat Sleep Console. They discuss the reported reduction in time to medical readiness for discharge and the proportion of treated infants who avoided scheduled opioid dosing.

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