Journal Club - Early Vitamin D: Can 800 IU Prevent BPD in Preterms?
The Incubator Channel · 25 Feb 2026 · 15 min
Summary
Ben and Daphna from The Incubator review an RCT testing whether early high-dose vitamin D (800 IU/day from day 1) reduces bronchopulmonary dysplasia in extremely preterm infants compared with starting at day 14. They discuss the physiological rationale linking vitamin D to lung development, impulse oscillometry for lung mechanics, secondary findings on metabolic bone disease, and why plausible physiology may not translate into clinical benefit.
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