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Journal Club - Should we start CPAP at 8 instead of 5 in the delivery room for very preterm infants?

The Incubator Channel · 16 Sept 2026 · 15 min

Summary

Ben and Daphna discuss the PHILODENDRON pilot RCT from Milan, which randomised 56 infants born at 26–29 weeks to delivery-room CPAP of 5 or 8 cmH2O to assess feasibility, safety and early physiological adaptation. They review findings on surfactant thresholds, air leaks and ventilation duration, weigh physiology against the data, and question whether such trials test the right question.

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