Journal Club - After LISA Does CPAP Perform as Well as NIMV Below 30 Weeks?
The Incubator Channel · 31 Aug 2026 · 19 min
Summary
Ben and Daphna discuss a multicentre JAMA Network Open noninferiority trial randomising infants born at 24 to 29 weeks to nasal CPAP or NIMV after less invasive surfactant administration, which stopped early for futility with higher noninvasive ventilation failure on CPAP. They explore the implications when surfactant is controlled for, an unexpected NEC signal, and whether guidelines need revisiting.
Third-party teaching is shown for education. Check it against your unit's guidance.