Journal Club - Antibiotic Use in HIE, A Tale of Two Strategies
The Incubator Channel · 13 Jan 2026 · 19 min
Summary
Ben and Daphna discuss a multicentre retrospective study from the European Journal of Pediatrics comparing Italian and Belgian cohorts to question routine empiric antibiotics in neonates undergoing therapeutic hypothermia for HIE. They cover a number needed to treat of 111 for one case of culture-proven sepsis, the diagnostic challenges of overlapping clinical markers, postnatal leukocyte trends, and whether selective antibiotic use is appropriate.
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