Journal Club - Could Longer Caffeine Treatment Reduce Hypoxia and Speed Discharge?
The Incubator Channel · 7 Jan 2026 · 12 min
Summary
Ben and Daphna review the ICAF randomised trial of extended caffeine therapy in preterm infants through 41 weeks postmenstrual age, covering study design, intermittent hypoxia outcomes across saturation thresholds and inflammatory biomarkers such as TNF-α. They also discuss safety signals including oxygen restart rates, length of stay and weight gain, and whether a targeted subgroup might benefit from continuing caffeine beyond usual stopping points.
Third-party teaching is shown for education. Check it against your unit's guidance.