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🔵 [PAS 2026] - Do the Tiniest Babies Survive More With Longer Antibiotic Courses?

The Incubator Channel · 26 Apr 2026 · 12 min

Summary

A neonatology fellow presents a PAS 2026 retrospective study of 296 infants born under 25 weeks, comparing standard 72-hour empiric antibiotics with a seven-day course for babies with placental chorioamnionitis. She reports lower mortality with longer courses at 22 and 23 weeks, no difference at 24 weeks, and an unexplained rise in spontaneous intestinal perforation in the prolonged antibiotic group.

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