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Journal Club - Early ibuprofen or waiting, does the PDA choice show up at two years?

The Incubator Channel · 28 Sept 2026 · 22 min

Summary

Ben and Daphna review the 24-month follow-up of the BeNeDuctus trial comparing expectant management with early ibuprofen for PDA in infants born before 28 weeks, placing it alongside Baby-OSCAR, TRIOCAPI, SMART-PDA and other trials. They discuss why a neutral result does not mean no PDA should be treated, and how targeted neonatal echocardiography and lung ultrasound are changing bedside PDA assessment.

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