Journal Club - Should We Treat the PDA Based on Size Alone? (SMART PDA Trial)
The Incubator Channel · 13 Jul 2026 · 42 min
Summary
Ben and Daphna discuss the SMART-PDA pilot RCT, which used comprehensive haemodynamic screening to selectively treat high-volume ductal shunts in infants born before 26 weeks, alongside a JAMA Network Open comparative effectiveness study of four pharmacotherapy regimens. They also share haemodynamic pearls on why left ventricular output, LA:Ao ratio and transductal velocity matter more than PDA diameter alone.
Third-party teaching is shown for education. Check it against your unit's guidance.