Journal Club - Is this the trial that brings probiotics back to the NICU?
The Incubator Channel · 12 Aug 2026 · 25 min
Summary
A journal club reviewing the Connection Study, a 2,158-infant phase 3 trial of the regulated L. reuteri product IBP-9414 for preventing NEC, covering its missed primary endpoints, the fall in all-cause mortality and the poor agreement between radiologists reading NEC films. The presenters discuss what a regulated probiotic could mean for NICU practice, particularly in the US context.
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