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Persistent Pulmonary Hypertension of Newborn Explained in the Easiest way

Paediatric Squad · 16 Feb 2026 · 19 min

Summary

An explainer on persistent pulmonary hypertension of the newborn, covering fetal circulation, the pathophysiology and vicious cycle of PPHN, causes such as meconium aspiration and congenital pneumonia, and diagnosis using pre- and post-ductal saturation differences. It then walks through stepwise management from inhaled nitric oxide to ECMO, aimed at junior doctors new to the NICU.

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Third-party teaching is shown for education. Check it against your unit's guidance.

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