Evidence · Systematic review or meta-analysis
Neurodevelopmental outcomes in preterm or low birth weight infants with germinal matrix-intraventricular hemorrhage: a meta-analysis.
- Allied health
- Intraventricular haemorrhage and white matter injury
- Medical
- Neurodevelopmental follow-up
- Neurology
- Nursing
Summary
This meta-analysis of 37 observational studies (32,370 children) examines near- and long-term neurodevelopmental outcomes in preterm or low birth weight infants with germinal matrix-intraventricular haemorrhage of differing severity. Compared with no IVH, even mild IVH was associated with higher rates of neurodevelopmental impairment, cerebral palsy, motor and cognitive delay, and hearing and visual impairment. Severe IVH conferred further increased risk and poorer developmental and IQ scores, while mild IVH was not associated with seizures or epilepsy. The findings support parental counselling and targeted follow-up and early intervention planning.
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- Open (Creative Commons)
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