Guidelines and research
Official guidance for neonatal care, the evidence behind it, and the latest neonatal research.
Open-access systematic reviews, meta-analyses and trials on neonatal topics, chosen for relevance and how widely they are cited. Evidence informs guidance but doesn't replace it.
- Octenidine or Sterile Water Cleansing and Late-Onset Sepsis in Neonates in the NICU: A Randomized Clinical Trial.Randomised trialJAMA Network Open2026Full text
- Data Collection and Harmonization in Preterm Respiratory Research: Recommendations and Insights From PELICAN.Research paperEuropean Respiratory Society (PELICAN Clinical Research Collaboration)2026Full text
- A Core Outcome Set for Family-Centered Care in Neonatal Intensive Care Settings: An International eDelphi Study and Online Consensus Meeting.Research paperChildren (Basel, Switzerland)2026Full text
- Optimizing Informed Consent for Australian Newborn Bloodspot Screening and Research: Consensus Workshop Insights and Recommendations.Research paperInternational Journal of Neonatal Screening2026Full text
- Neonatal Hypoglycemia: A Systematic Review of International and Local Clinical Guidelines with Clinical Implications.Systematic review or meta-analysisJournal of Clinical Medicine2026Full text
- Candidemia and invasive candidiasis in children and neonates: transposing adult diagnostic recommendations may undermine end-organ screening.CommentaryThe Brazilian Journal of Infectious Diseases2026Full text
- Extended Barrier Precautions vs Hand Hygiene Alone and Neonatal Sepsis in Intensive Care Patients: The BALTIC Cluster-Randomized Clinical Trial.Randomised trialJAMA Network Open2026Full text
- Nurse-Driven Quality Indicators for Neonatal Intensive Care: A Delphi Consensus on Family-Integrated Priorities in NICUs.Research paperAdvances in Neonatal Care (NANN journal)2026Full text
- Assessment of compliance to the guidelines on nutritional support in a neonatal intensive care unit: association with an electronic health Records implementation.Research paperBMC Medical Informatics and Decision Making2026Full text
- Pulmonary Hypertension Association with Mortality in Newborns with Giant Omphalocele: A Systematic Review and Meta-Analysis.Systematic review or meta-analysisNeonatology2026Full text
- 2025 American and European Guidelines on Neonatal Resuscitation: Concordance and Differences.Review articleNeonatology2026Full text
- Medical Skills Curriculum for Interdisciplinary Neonatal Transport Teams: A European Delphi Consensus Study.Research paperActa Paediatrica2026Full text
- Clinicians' recommendations on neonatal bathing and skin care in the context of atopic dermatitis prevention: An EAACI task force report.Research paperEAACI2026
- Knowledge and Observed Practices of Hospital-Acquired Infection Prevention Guidelines Among Nurses Working in Neonatal Intensive Care Units in Jordan: A Cross-Sectional Observational Study.Research paperTheScientificWorldJournal2026Full text
- Randomised crossover trial of neurally adjusted ventilatory assist (NAVA) for neonates with congenital diaphragmatic hernias: the NAN-C study.Randomised trialEuropean Journal of Pediatrics2026Full text
- Implementation of national guidelines on antenatal magnesium sulfate for neonatal neuroprotection: extended evaluation of the effectiveness and cost-effectiveness of the National PReCePT Programme in England.Research paperBMJ Quality & Safety2026Full text
- Optimizing platelet transfusion thresholds in preterm infants: a systematic review and narrative synthesis of impacts on survival and neurodevelopment.Systematic review or meta-analysisBlood Transfusion (journal)2026Full text
- How consistent are recent neonatal resuscitation guidelines?Review articleResuscitation Plus2026Full text
- The comparative effects of prenatal exposure to methadone versus buprenorphine for opioid use disorder on neonatal outcomes: a systematic review and meta-analysis.Systematic review or meta-analysisBMC Pregnancy and Childbirth2026Full text
- Hyperbilirubinemia in premature infants <35 weeks' gestation: A chronologic age format for graphing consensus-based recommendations.Research paperJournal of Perinatology2026
- Risk Factors for Postnatal Growth Faltering and Undernutrition at Discharge in Very Preterm Infants: A Retrospective Study Applying the ESPGHAN Consensus Definitions.Research paperNutrients2026Full text
- Devices for Neonatal Peripheral Catheterization and Tip Confirmation: A Systematic Review and Meta-Analysis.Systematic review or meta-analysisNeonatology2026Full text
- Treatment of Urinary Tract Infections in Neonates and Young Infants: Evidence and Recommendations.Review articleAntibiotics (Basel, Switzerland)2026Full text
- Development and implementation of educational modules on management of neonates with critical congenital heart disease in the delivery room (LEARN-CHD).Randomised trialJournal of Perinatology2026Full text
- Mucopolysaccharidosis Type II Screening, Diagnosis, and Management: A Literature Review and Practical Recommendations for Newborn Screening Programs and Health Care Providers to Support Families and Improve Outcomes.Review articleInternational Journal of Neonatal Screening2026Full text
- Effect of adherence to nutrition guidelines and use of fortification of feeds on the growth of late preterm neonates.Research paperPLOS ONE2026Full text
- Perioperative outcomes in primary neonatal pullthrough versus pullthrough in older children with Hirschsprung disease: a systematic review and meta-analysis.Systematic review or meta-analysisScientific Reports2026Full text
- Consensus-based eligibility criteria and component definitions for neonatal and infant enhanced recovery pathway: a multidisciplinary delphi study.Research paperJournal of Perinatology2026Full text
- The development of a consensus-based curriculum for a Bespoke Online Neonatal Education for Transfers (BONNETs) course.Research paperBMC Medical Education2026Full text
- Umbilical cord management in newborn resuscitation: a systematic review and meta-analysis.Systematic review or meta-analysisPediatric Research2025Full text
- Association of patent ductus arteriosus treatment in extremely low gestational age neonates with two year kidney outcomes: a secondary analysis of the preterm erythropoietin neuroprotection trial (PENUT).Research paperBMC Nephrology2025Full text
- Neonatal therapy principles during transition from neonatal intensive care unit to home: A modified Delphi study.Research paperDevelopmental Medicine and Child Neurology2025Full text
- Evaluation of Newborn Screening for Diseases Using C5-OH as a Marker: Systematic Review of the Literature and Evaluation of 17 Years of C5-OH Screening in the Netherlands.Systematic review or meta-analysisJournal of inherited metabolic disease2025Full text
- Association between transfer for surgery and mortality and disability among neonates in high income countries-A systematic review with meta-analysis.Systematic review or meta-analysisPLOS ONE2025Full text
- Respiratory distress in late-preterm neonates: from controversy to consensus - a survey of regional advisory boards and neonatologists in France.Research paperBMJ Paediatrics Open2025Full text
- Determinants of neonatal mortality in sub-Saharan Africa: systematic review and meta-analysis of adverse newborn conditions.Systematic review or meta-analysisBMC Public Health2025Full text
- The efficiency and safety of low-dose intravenous indomethacin for closure of patent ductus arteriosus in preterm neonate: a randomized controlled trial.Randomised trialScientific Reports2025Full text
- Growth after pediatric and neonatal acute kidney injury: a meta-analysis.Systematic review or meta-analysisPediatric Nephrology (journal)2025Full text
- Active versus restrictive approach to isolated hypotension in preterm neonates: A Systematic Review, Meta-analysis and GRADE based Clinical Practice Guideline.Systematic review or meta-analysisPLOS ONE2025Full text
- Prevention and Treatment of Neonatal Infections in Facility and Community Settings of Low- and Middle-Income Countries: A Descriptive Review.Review articleNeonatology2025Full text
- Adherence to guidelines on quality neonatal resuscitation practices among healthcare professionals in Ghana: an observational study.Research paperBMJ Open2025Full text
- Facilitators and barriers to the practice of neonatal family integrated care from the perspective of healthcare professionals: a systematic review.Systematic review or meta-analysisArchives of Disease in Childhood: Fetal and Neonatal Edition2025Full text
- Acute Kidney Injury and Neurodevelopmental Outcomes in Extremely Premature Neonates: A Secondary Analysis of a Randomized Clinical Trial.Research paperJAMA Network Open2025Full text
- Active Treatment vs Expectant Management of Patent Ductus Arteriosus in Preterm Infants: A Meta-Analysis.Systematic review or meta-analysisJAMA Pediatrics2025Full text
- Inborn errors of metabolism in neonates and pediatrics on varying dialysis modalities: a systematic review and meta-analysis.Systematic review or meta-analysisPediatric Nephrology2025Full text
- Real-time ultrasound to assess the umbilical catheter position in neonates: a randomized, controlled trial.Randomised trialJournal of Perinatology2025Full text
- Parents', Families', Communities' and Healthcare Professionals' Experiences of Care Following Neonatal Death in Healthcare Facilities in LMICs: A Systematic Review and Meta-Ethnography.Systematic review or meta-analysisBJOG: an international journal of obstetrics and gynaecology2025Full text
- Socioeconomic disparities in the postnatal growth of preterm infants: a systematic review.Systematic review or meta-analysisPediatric Research2025Full text
- Clinical Overview of Group B Strep DiseaseOtherCenters for Disease Control and Prevention (CDC)2025May 1, 2025Full text
- Comparing Malposition and Complications Associated with Ultrasound-Guided versus Radiography-Guided Central Catheter Tip-Position in Neonates: A Systematic Review and Meta-Analysis.Systematic review or meta-analysisNeonatology2025Full text
- A novel human milk fortifier supports adequate growth in very low birth weight infants: a non-inferiority randomised controlled trial.Randomised trialArchives of Disease in Childhood. Fetal and Neonatal Edition2025Full text
- A formal statechart model of immediate neonatal adaptation guidelines.Research paperHeliyon2025Full text
- Comprehensive evaluation of risk factors for intraventricular hemorrhage in preterm neonates: a systematic review and meta-analysis.Systematic review or meta-analysisEuropean Journal of Medical Research2025Full text
- Platelet characteristics in extremely preterm infants after fatty acid supplementation: a randomized controlled trial.Randomised trialPediatric Research2025Full text
- Immediate or early skin-to-skin contact for mothers and their healthy newborn infants.Systematic review or meta-analysisCochrane2025Full text
- Ethics and end-of-life in pediatric and neonatal ICUs: a systematic review of recommendations.Systematic review or meta-analysisBMC Palliative Care2025Full text
- Timing of hydrocortisone therapy in neonates with shock: a systematic review, meta-analysis, and clinical practice guideline.Systematic review or meta-analysisFrontiers in Pediatrics2025Full text
- International treatment outcomes of neonates on extracorporeal membrane oxygenation (ECMO) with persistent pulmonary hypertension of the newborn (PPHN): a systematic review.Systematic review or meta-analysisJournal of Cardiothoracic Surgery2024Full text
- Ventilatory Assistance Before Umbilical Cord Clamping in Extremely Preterm Infants: A Randomized Clinical Trial.Randomised trialJAMA Network Open2024Full text
- Effectiveness and family experiences of interventions promoting partnerships between families and pediatric and neonatal intensive care units: a mixed methods systematic review.Systematic review or meta-analysisJBI Evidence Synthesis2024Full text