Evidence · Systematic review or meta-analysis
Perioperative outcomes in primary neonatal pullthrough versus pullthrough in older children with Hirschsprung disease: a systematic review and meta-analysis.
- Bowel obstruction
- Medical
- Nursing
- Nutrition and gastrointestinal
- Surgical conditions
Summary
This systematic review and meta-analysis compares perioperative and functional outcomes of primary pullthrough for Hirschsprung disease performed in the neonatal period versus after one month of age. Twenty observational studies including 3197 patients were analysed. Later pullthrough was associated with shorter postoperative stay and less sepsis, perianal excoriation, Hirschsprung-associated enterocolitis and anal stenosis, while neonatal surgery had shorter operative times. The authors note low-quality evidence and inconsistent outcome definitions, calling for a large prospective study.
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- Open (Creative Commons)
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