Evidence · Systematic review or meta-analysis
Comparing Malposition and Complications Associated with Ultrasound-Guided versus Radiography-Guided Central Catheter Tip-Position in Neonates: A Systematic Review and Meta-Analysis.
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Summary
This systematic review and meta-analysis compares ultrasound-guided with radiography-guided confirmation of central catheter tip position in neonates, including eight studies (four RCTs and four non-randomised studies, 1,322 infants). Outcomes included malposition, number of X-rays, procedure time, catheter manipulation, tamponade, extravasation, occlusion and sepsis. Ultrasound guidance was associated with fewer malpositions and less radiation exposure, with no clear differences in procedure time, manipulation or sepsis. All evidence was rated low certainty, and further research is recommended.
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