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Evidence · Systematic review or meta-analysis

Devices for Neonatal Peripheral Catheterization and Tip Confirmation: A Systematic Review and Meta-Analysis.

Systematic review or meta-analysisNeonatology2026Full text
  • Arrhythmias
  • Cardiovascular
  • Families and professional practice
  • Line and device care
  • Medical
  • Nursing
  • Pain and comfort

Summary

This systematic review and meta-analysis of 12 randomised controlled trials (1,251 neonates) compares device-assisted techniques, such as ultrasound and other visualisation aids, with standard technique for neonatal peripheral intravenous catheterisation, PICC placement and catheter tip confirmation. Device assistance may improve first-attempt success and shorten procedure time, and likely reduces haematoma, bleeding and phlebitis. Evidence on thrombosis, catheter-related bloodstream infection and arrhythmia is of very low certainty. The authors call for high-quality trials with standardised outcome measures.

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