Evidence · Systematic review or meta-analysis
Determinants of neonatal mortality in sub-Saharan Africa: systematic review and meta-analysis of adverse newborn conditions.
- Delivery room and stabilisation
- Early-onset sepsis
- Hypoglycaemia
- Hypoxic-ischaemic encephalopathy and cooling
- Infection
- Infection prevention
- Late-onset sepsis
- Medical
- Metabolic, endocrine and renal
- Neurology
- Nursing
- Respiratory
- Respiratory distress syndrome and surfactant
- Thermoregulation
Summary
This systematic review and meta-analysis of 36 observational studies from sub-Saharan Africa examines the association between adverse newborn conditions and neonatal mortality. Preterm birth, low birth weight, birth asphyxia, respiratory distress syndrome, hypothermia, hypoglycaemia and neonatal sepsis were each associated with increased odds of death. The authors highlight the need to strengthen essential newborn care alongside maternal services such as antenatal care, nutrition in pregnancy, quality intrapartum care and infection prevention. It is most relevant to clinicians and planners working in low-resource settings.
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- Licence:
- Open (Creative Commons)
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