Evidence · Research paper
Implementation of national guidelines on antenatal magnesium sulfate for neonatal neuroprotection: extended evaluation of the effectiveness and cost-effectiveness of the National PReCePT Programme in England.
- Families and professional practice
- Intraventricular haemorrhage and white matter injury
- Medical
- Neurodevelopmental follow-up
- Neurology
- Nursing
- Quality improvement
Summary
This quasi-experimental longitudinal study extends the evaluation of the National PReCePT quality improvement programme, which supported implementation of NICE guidance on antenatal magnesium sulfate for neuroprotection in preterm labour across England. Using National Neonatal Research Database data, it examines longer-term uptake over four years, use in later preterm births, the impact of the COVID-19 pandemic and comparison with Scotland and Wales. Magnesium sulfate use rose substantially in England, and the programme was associated with improved uptake and was cost-effective. It is relevant to perinatal teams working on preterm brain protection and national quality improvement.
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- Open (Creative Commons)
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