Evidence · Systematic review or meta-analysis
Effect of Different Types of Diagnostic Criteria for Gestational Diabetes Mellitus on Adverse Neonatal Outcomes: A Systematic Review, Meta-Analysis, and Meta-Regression.
- Hypoglycaemia
- Jaundice and phototherapy
- Medical
- Metabolic, endocrine and renal
- Postnatal and transitional care
Summary
Systematic review and meta-analysis of 55 population-based studies comparing different diagnostic criteria for gestational diabetes mellitus and their association with adverse neonatal outcomes. Across all criteria groups, infants of mothers with GDM had higher risks of macrosomia, hyperbilirubinaemia, respiratory distress syndrome, neonatal hypoglycaemia, NICU admission, preterm birth and birth trauma than infants of mothers without GDM. Meta-regression showed similar magnitude of neonatal risk regardless of which diagnostic criteria were used. Mainly informs obstetric screening policy, with relevance to anticipating neonatal complications in infants of diabetic mothers.
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