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Evidence · Research paper

Impact of implementation of 2019 European respiratory distress syndrome guidelines on bronchopulmonary dysplasia in very preterm infants.

Research paperItalian Journal of Pediatrics2024Full text
  • Breast milk and breastfeeding
  • Bronchopulmonary dysplasia
  • Cardiovascular
  • CPAP and high flow
  • Mechanical ventilation
  • Medical
  • Nursing
  • Patent ductus arteriosus
  • Quality improvement
  • Respiratory
  • Respiratory distress syndrome and surfactant

Summary

Retrospective before-and-after cohort study of 593 very preterm infants (<32 weeks) assessing the effect of implementing the 2019 European Consensus Guidelines on RDS management on bronchopulmonary dysplasia. After implementation, practice changes included more antenatal corticosteroid use, less invasive ventilation, more volume-targeted and synchronised non-invasive ventilation, higher surfactant doses, shorter antibiotic exposure, more breast milk and earlier treatment of haemodynamically significant PDA. BPD incidence fell overall, though the authors note ongoing quality improvement is needed for infants under 28 weeks or 1,000 g.

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