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Evidence · Systematic review or meta-analysis

Iron Deficiency and Iron Homeostasis in Low Birth Weight Preterm Infants: A Systematic Review.

Systematic review or meta-analysisNutrients (MDPI)2019Over 5 years oldFull text
  • Allied health
  • Anaemia and transfusion
  • Enteral feeding
  • Growth
  • Jaundice and haematology
  • Medical
  • Nursing
  • Nutrition and gastrointestinal

This paper is from 2019, more than five years ago. Newer evidence may have been published since.

Summary

This systematic review examines iron status, iron deficiency and iron homeostasis in preterm and low birth weight infants, who have higher iron requirements because of rapid postnatal growth. It considers both the risk of iron deficiency and iron deficiency anaemia and the potential harms of iron excess in infants with immature antioxidant defences. Studies published between 2008 and 2018 were assessed, using PRISMA-adapted methods and PICO criteria, for the impact of iron status on growth and development. It is relevant to clinicians planning iron supplementation and nutritional follow-up for preterm infants.

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