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Evidence · Systematic review or meta-analysis

Maternal and Neonatal Outcomes of Pregnancies in Women With Congenital Heart Disease: A Meta-Analysis.

Systematic review or meta-analysisJournal of the American Heart Association2021Full text
  • Arrhythmias
  • Cardiovascular
  • Congenital heart disease
  • Medical

Summary

This meta-analysis of 32 studies published 2007–2019 examines maternal and neonatal outcomes of pregnancy in women with congenital heart disease, grouped by lesion severity (mild, moderate, severe). Neonatal mortality and morbidity, including preterm birth and small for gestational age, rose with increasing maternal lesion severity, as did maternal arrhythmia, heart failure and caesarean section. Most pregnancies had successful outcomes. The findings support preconception counselling and perinatal planning for women with congenital heart disease.

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