Evidence · Randomised trial
Bifidobacterium and enteral feeding in preterm infants: cluster-randomized trial.
- Allied health
- Enteral feeding
- Growth
- Infection
- Late-onset sepsis
- Medical
- Necrotising enterocolitis
- Nursing
- Nutrition and gastrointestinal
This paper is from 2014, more than five years ago. Newer evidence may have been published since.
Summary
Cluster-randomised, double-blind, placebo-controlled trial across 19 Japanese hospitals evaluating Bifidobacterium bifidum OLB6378 given within 48 hours of birth to very low-birthweight infants. The primary outcome was time to establishment of full enteral feeding, with morbidity and somatic growth before discharge as secondary outcomes. Infants receiving the probiotic reached full enteral feeds earlier than those given placebo, without an increase in adverse effects. Relevant to neonatal teams considering probiotic use and feeding advancement in preterm infants.
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- Licence:
- Open (Creative Commons)
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