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Evidence · Systematic review or meta-analysis

Benefits of umbilical cord milking versus delayed cord clamping on neonatal outcomes in preterm infants: A systematic review and meta-analysis.

Systematic review or meta-analysisPLoS ONE2018Over 5 years oldFull text
  • Cord management
  • Delivery room and stabilisation
  • Intraventricular haemorrhage and white matter injury
  • Medical
  • Neurodevelopmental follow-up
  • Neurology
  • Nursing
  • Preterm stabilisation

This paper is from 2018, more than five years ago. Newer evidence may have been published since.

Summary

Systematic review and meta-analysis of randomised trials comparing umbilical cord milking with delayed cord clamping in infants born before 37 weeks' gestation. Only two trials (255 infants, 23 to 32 weeks) were included, with low-quality evidence. Cord milking was associated with fewer intraventricular haemorrhages and better Bayley cognitive and language outcomes at 2 years, with no difference in in-hospital mortality or transfusion need. The small evidence base predates later safety concerns about cord milking in extremely preterm infants.

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