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Evidence · Systematic review or meta-analysis

Cerebellar Hemorrhage in Preterm Infants: A Meta-Analysis on Risk Factors and Neurodevelopmental Outcome.

Systematic review or meta-analysisFrontiers in Physiology2019Over 5 years oldFull text
  • Cardiovascular
  • Intraventricular haemorrhage and white matter injury
  • Medical
  • Neurodevelopmental follow-up
  • Neurology
  • Patent ductus arteriosus

This paper is from 2019, more than five years ago. Newer evidence may have been published since.

Summary

This systematic review and meta-analysis examines perinatal risk factors and neurodevelopmental outcomes of cerebellar haemorrhage in preterm infants, drawing on 15 studies. Lower gestational age and birth weight, together with markers of neonatal illness such as intubation at birth, hypotension, PDA, IVH, sepsis, NEC and BPD, were associated with cerebellar haemorrhage. Cerebellar haemorrhage was linked to delayed mental and psychomotor development and higher rates of cerebral palsy. It is relevant to clinicians caring for very preterm infants and planning neuroimaging and follow-up.

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