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Evidence · Systematic review or meta-analysis

Prenatal, Perinatal and Neonatal Risk Factors for Intellectual Disability: A Systemic Review and Meta-Analysis.

Systematic review or meta-analysisPLoS ONE2016Over 5 years oldFull text
  • Education and simulation
  • Families and professional practice
  • Medical
  • Neurodevelopmental follow-up
  • Neurology

This paper is from 2016, more than five years ago. Newer evidence may have been published since.

Summary

Systematic review and meta-analysis of 17 studies examining prenatal, perinatal and neonatal risk factors for non-genetic intellectual disability. Ten maternal prenatal factors, including maternal age, education, substance use, diabetes, hypertension, epilepsy and asthma, were associated with increased risk. Preterm birth, male sex and low birth weight were the perinatal and neonatal factors linked to intellectual disability. Relevant to neonatal clinicians counselling families and planning neurodevelopmental follow-up.

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