Evidence · Randomised trial
Nutritional Evaluation and Optimisation in Neonates: a randomized, double-blind controlled trial of amino acid regimen and intravenous lipid composition in preterm parenteral nutrition.
- Allied health
- Growth
- Jaundice and haematology
- Jaundice and phototherapy
- Medical
- Nursing
- Nutrition and gastrointestinal
- Parenteral nutrition
This paper is from 2016, more than five years ago. Newer evidence may have been published since.
Summary
The NEON trial is a multicentre, double-blind, 2-by-2 factorial randomised controlled trial in very preterm infants comparing immediate full recommended parenteral amino acid intake with incremental introduction, and a multicomponent SMOF lipid emulsion with a soybean oil-based emulsion. Outcomes included body composition and intrahepatocellular lipid content. The authors concluded that immediate high amino acid delivery did not improve body composition or growth to term and may be harmful. The abstract text is partly truncated, so full results should be checked in the source.
Summary written for NICUlearn. Always read the original.
- Licence:
- Open (Creative Commons)
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