Evidence · Randomised trial
Randomised trial of cord clamping and initial stabilisation at very preterm birth.
- Cord management
- Delivery room and stabilisation
- Intraventricular haemorrhage and white matter injury
- Medical
- Nursing
- Preterm stabilisation
This paper is from 2018, more than five years ago. Newer evidence may have been published since.
Summary
This UK multicentre randomised trial (the Cord Pilot Trial) compared deferred cord clamping of at least 2 minutes with neonatal stabilisation performed with the cord intact, against clamping within 20 seconds followed by stabilisation, in births before 32 weeks. It enrolled 261 women and 276 babies across eight tertiary maternity units. The primary outcomes were intraventricular haemorrhage and death before discharge. Mortality was lower with deferred clamping, although the confidence interval crossed zero, and there was no clear difference in IVH, so the authors call for a larger definitive trial.
Summary written for NICUlearn. Always read the original.
- Licence:
- Open (Creative Commons)
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