Evidence · Systematic review or meta-analysis
Risk of Early-Onset Neonatal Group B Streptococcal Disease With Maternal Colonization Worldwide: Systematic Review and Meta-analyses.
- Early-onset sepsis
- Infection
- Medical
This paper is from 2017, more than five years ago. Newer evidence may have been published since.
Summary
This systematic review and meta-analysis, part of a series on the global burden of group B streptococcal disease, estimates the risk of early-onset GBS disease in neonates born to rectovaginally colonised mothers. It pooled 30 studies including over 20,000 colonised pregnant women and examined how risk varies with intrapartum antibiotic prophylaxis coverage. Risk was around 1% in settings without a prophylaxis policy and fell linearly as prophylaxis coverage increased. It is useful background for clinicians assessing early-onset sepsis risk and perinatal GBS prevention strategies.
Summary written for NICUlearn. Always read the original.
- Licence:
- Open (Creative Commons)
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