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Evidence · Systematic review or meta-analysis

Efficacy of Donated Milk in Early Nutrition of Preterm Infants: A Meta-Analysis.

Systematic review or meta-analysisNutrients2022Full text
  • Allied health
  • Breast milk and breastfeeding
  • Enteral feeding
  • Growth
  • Medical
  • Necrotising enterocolitis
  • Nursing
  • Nutrition and gastrointestinal
  • Parenteral nutrition

Summary

Systematic review and meta-analysis of 11 randomised controlled trials (1390 infants) comparing donated breast milk with formula in the early nutrition of preterm infants. Donor milk was associated with a lower incidence of necrotising enterocolitis, shorter parenteral nutrition duration and shorter time to full enteral feeds. Formula was associated with better weight gain, head growth and length, and a quicker return to birth weight. The authors suggest that fortifying donor milk may achieve growth comparable to formula.

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