Evidence · Systematic review or meta-analysis
Fish oil-containing lipid emulsions prevention on parenteral nutrition-associated cholestasis in very low birth weight infants: a meta-analysis.
- Allied health
- Medical
- Nutrition and gastrointestinal
- Parenteral nutrition
Summary
Meta-analysis of 11 randomised controlled trials comparing fish oil-containing with fish oil-free lipid emulsions for preventing parenteral nutrition-associated cholestasis in very low birth weight infants. Pooled data suggested fish oil-containing emulsions reduced cholestasis, with the effect most evident when parenteral nutrition exceeded 14 days and in extremely low birth weight infants. The authors note further studies are needed before definitive conclusions. Relevant to neonatal clinicians, dietitians and pharmacists prescribing parenteral nutrition.
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- Open (Creative Commons)
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