Evidence · Systematic review or meta-analysis
Association between perinatal hypoxic-ischemia and periventricular leukomalacia in preterm infants: A systematic review and meta-analysis.
- Hypoxic-ischaemic encephalopathy and cooling
- Intraventricular haemorrhage and white matter injury
- Medical
- Neurology
- Seizures
This paper is from 2017, more than five years ago. Newer evidence may have been published since.
Summary
Systematic review and meta-analysis of 15 studies (12,851 participants) examining perinatal hypoxic-ischaemia-related risk factors for periventricular leukomalacia in preterm infants. Fourteen potential risk factors were analysed using pooled odds ratios. Factors identified as associated with PVL included maternal oligohydramnios, neonatal acidaemia and low 1-minute Apgar score. The authors call for large prospective studies to validate the findings.
Summary written for NICUlearn. Always read the original.
- Licence:
- Open (Creative Commons)
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