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Evidence · Systematic review or meta-analysis

Outcome reporting in neonates experiencing withdrawal following opioid exposure in pregnancy: a systematic review.

Systematic review or meta-analysisTrials2020Over 5 years oldFull text
  • Comfort and nursing care
  • Families and professional practice
  • Medical
  • Neonatal abstinence syndrome
  • Nursing
  • Postnatal and transitional care

This paper is from 2020, more than five years ago. Newer evidence may have been published since.

Summary

Systematic review of outcomes reported in studies of pharmacological and non-pharmacological interventions for neonatal withdrawal after in utero opioid exposure, covering literature from 2007 to 2017. Forty-seven studies were included, with duration of pharmacotherapy, length of hospital stay and withdrawal symptoms most often reported. Outcome definitions and timing were heterogeneous, and no studies involved parents in outcome selection. The authors argue for development of a core outcome set to support evidence synthesis and guideline development.

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