Evidence · Systematic review or meta-analysis
A systematic review on the impact of gestational Lyme disease in humans on the fetus and newborn.
- Congenital infections
- Infection
- Jaundice and haematology
- Jaundice and phototherapy
- Medical
This paper is from 2018, more than five years ago. Newer evidence may have been published since.
Summary
This systematic review and meta-analysis summarises global literature on adverse fetal and newborn outcomes associated with gestational Lyme disease. It identified 45 studies, including case reports and epidemiological studies, describing outcomes such as miscarriage, fetal and newborn death, and abnormal neonatal findings. Evidence for transplacental transmission of Borrelia burgdorferi was limited, and epidemiological findings were inconsistent, though treated pregnancies had fewer adverse outcomes than untreated ones. The authors highlight knowledge gaps and support prompt diagnosis and treatment of Lyme disease in pregnancy.
Summary written for NICUlearn. Always read the original.
- Licence:
- Open (Creative Commons)
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