Evidence · Systematic review or meta-analysis
The Impact of Interventions to Prevent Neonatal Healthcare-associated Infections in Low- and Middle-income Countries: A Systematic Review.
- Comfort and nursing care
- Infection
- Infection prevention
- Late-onset sepsis
- Line and device care
- Medical
- Nursing
- Quality improvement
- Skin care
Summary
This systematic review examines single and bundled infection prevention and control interventions aimed at reducing hospital-acquired bloodstream infections in neonatal units in low- and middle-income countries. It summarises 27 studies covering skin care such as emollients, gastrointestinal interventions such as lactoferrin and probiotics, chlorhexidine cord care, kangaroo mother care and device-associated infection bundles. Bundles targeting catheter- and ventilator-associated infections showed the most consistent benefit, but the overall evidence base is limited and few studies come from low-income settings or sub-Saharan Africa. It is relevant to clinicians and nurses planning infection prevention strategies in resource-limited neonatal care.
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- Licence:
- Open (Creative Commons)
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