Evidence · Systematic review or meta-analysis
Noninvasive high-frequency oscillatory ventilation as respiratory support in preterm infants: a meta-analysis of randomized controlled trials.
- CPAP and high flow
- Mechanical ventilation
- Medical
- Nursing
- Respiratory
This paper is from 2019, more than five years ago. Newer evidence may have been published since.
Summary
Meta-analysis of eight randomised controlled trials (463 infants) comparing noninvasive high-frequency oscillatory ventilation (nHFOV) with nasal CPAP or biphasic CPAP for respiratory support in preterm infants. nHFOV was associated with a lower risk of intubation and more effective carbon dioxide clearance. The authors highlight uncertainty about optimal ventilator settings, effects in extremely preterm infants and long-term safety, calling for larger trials.
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- Licence:
- Open (Creative Commons)
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