Evidence · Systematic review or meta-analysis
Antacid therapy for gastroesophageal reflux in preterm infants: a systematic review.
- Allied health
- Enteral feeding
- Fluids and electrolytes
- Medical
- Metabolic, endocrine and renal
- Nursing
- Nutrition and gastrointestinal
This paper is from 2018, more than five years ago. Newer evidence may have been published since.
Summary
This systematic review examines the efficacy and safety of antacid therapy, including proton pump inhibitors such as omeprazole, for preterm infants with symptoms of gastro-oesophageal reflux. Six studies were included, but meta-analysis was not possible because of heterogeneity in interventions and outcomes. The authors conclude there is insufficient evidence to determine whether antacids are effective or safe in this population. They advise caution when prescribing antacids to preterm infants and call for further research.
Summary written for NICUlearn. Always read the original.
- Licence:
- Open (Creative Commons)
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