Meconium-stained amniotic fluid and neonatal morbidity in nulliparous patients with prolonged pregnancy.

Summary

Secondary analysis of the French NOCETER randomised trial examining the association between meconium-stained amniotic fluid and severe neonatal morbidity in nulliparous women at 41+0 weeks onwards with singleton cephalic pregnancies. Among 1274 included patients, amniotic fluid was classified as normal, thin or thick meconium-stained. Thick meconium-stained fluid was associated with higher rates of a composite severe neonatal morbidity outcome, whereas thin meconium was not. The findings are relevant to perinatal risk assessment and delivery-room preparedness for neonatal teams.

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