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The correlation between prelabour rupture of the membranes and neonatal infectious diseases, and the evaluation of guideline implementation in China: a multi-centre prospective cohort study.

Research paperThe Lancet Regional Health – Western Pacific2020Over 5 years oldFull text
  • Early-onset sepsis
  • Infection
  • Medical

This paper is from 2020, more than five years ago. Newer evidence may have been published since.

Summary

Multi-centre prospective cohort study of nearly 16,000 deliveries across three Chinese women's and children's hospitals describing the epidemiology of prelabour rupture of membranes (PROM). It examines the association between PROM and early neonatal infections, including early-onset sepsis and pneumonia, in term and preterm infants. It also evaluates whether adherence to national PROM guidance, such as timely induction of labour at term and antibiotic use in preterm PROM, was associated with fewer neonatal infectious outcomes.

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