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Evidence · Systematic review or meta-analysis

Oximetry and neonatal examination for the detection of critical congenital heart disease: a systematic review and meta-analysis.

Systematic review or meta-analysisF1000Research2019Over 5 years oldFull text
  • Cardiovascular
  • Congenital heart disease
  • Medical
  • Newborn examination
  • Nursing
  • Postnatal and transitional care

This paper is from 2019, more than five years ago. Newer evidence may have been published since.

Summary

This systematic review and meta-analysis compares pulse oximetry combined with physical examination against physical examination alone for detecting critical congenital heart disease in newborns. Five studies including over 400,000 newborns were analysed. Adding oximetry to the clinical examination markedly improved sensitivity while keeping specificity high. The authors highlight its value as a screening test, particularly in low- and middle-income settings.

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