Evidence · Randomised trial
A Mixed Lipid Emulsion for Prevention of Parenteral Nutrition Associated Cholestasis in Extremely Low Birth Weight Infants: A Randomized Clinical Trial.
- Allied health
- Jaundice and haematology
- Jaundice and phototherapy
- Medical
- Nursing
- Nutrition and gastrointestinal
- Parenteral nutrition
This paper is from 2018, more than five years ago. Newer evidence may have been published since.
Summary
Single-centre double-blind randomised trial of 230 extremely low birth weight infants in a level IV NICU comparing a mixed lipid emulsion (soybean, MCT, olive and fish oil) with a soybean oil-based emulsion for parenteral nutrition. The primary outcome was parenteral nutrition associated cholestasis. Cholestasis was less frequent with the mixed emulsion, but the difference was not statistically significant. No significant effect on other neonatal morbidities was found.
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- Open (Creative Commons)
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