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Evidence · Research paper

Association between gestational age at birth, antenatal corticosteroids, and outcomes at 5 years: multiple courses of antenatal corticosteroids for preterm birth study at 5 years of age (MACS-5).

Research paperBMC Pregnancy and Childbirth2014Over 5 years oldFull text
  • Delivery room and stabilisation
  • Medical
  • Neurodevelopmental follow-up
  • Neurology
  • Preterm stabilisation

This paper is from 2014, more than five years ago. Newer evidence may have been published since.

Summary

Secondary analysis of the MACS randomised trial and its 5-year follow-up, examining how gestational age at birth relates to outcomes at 5 years in children exposed in utero to single versus multiple courses of antenatal corticosteroids. The cohort comprised 1719 children grouped by gestational age at birth. Gestational age was strongly associated with the primary outcome of death or neurodevelopmental impairment. The abstract text is truncated, so detailed findings are unavailable.

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