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Evidence · Research paper

Prolonged Rupture of Membranes, Neonatal Outcomes and Management Guidelines.

Research paperJournal of Clinical Medicine Research2019Over 5 years oldFull text
  • Early-onset sepsis
  • Infection
  • Medical
  • Nursing
  • Postnatal and transitional care

This paper is from 2019, more than five years ago. Newer evidence may have been published since.

Summary

Retrospective single-centre study of 176 neonates of 34 weeks' gestation or more admitted because of prolonged rupture of membranes, all born to mothers with unknown group B streptococcus status. Infants were categorised as ill appearing, well or equivocal at birth, and the sepsis risk calculator was applied retrospectively. Most infants were asymptomatic; a minority had culture-positive or culture-negative sepsis, with sepsis more common in the ill-appearing group. The authors argue for a protocol combining multiple assessment methods and clinical follow-up to avoid missing true sepsis while reducing unnecessary antibiotic use.

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