Evidence · Systematic review or meta-analysis
Adverse maternal, fetal, and newborn outcomes among pregnant women with SARS-CoV-2 infection: an individual participant data meta-analysis.
- Congenital infections
- Infection
- Mechanical ventilation
- Medical
- Respiratory
Summary
An individual participant data meta-analysis of 12 studies across 12 countries (13,136 pregnant women) comparing outcomes of pregnancies with and without SARS-CoV-2 infection. Infection was associated with increased maternal mortality, intensive care admission, mechanical ventilation, pneumonia and thromboembolic disease. Neonates born to infected women were more likely to be admitted to neonatal care, born preterm or moderately preterm, and of low birth weight, though infection was not linked to stillbirth or intrauterine growth restriction. Useful perinatal evidence for clinicians counselling families and anticipating neonatal admissions.
Summary written for NICUlearn. Always read the original.
- Licence:
- Open (Creative Commons)
The full text of this openly licensed paper is available to NICUlearn members, and Neeky can answer questions from it.
Guidelines are shown for education. Follow your unit's own guidance and senior advice.