Evidence · Systematic review or meta-analysis
Complications and mortality of venovenous extracorporeal membrane oxygenation in the treatment of neonatal respiratory failure: a systematic review and meta-analysis.
- Cardiovascular
- Intraventricular haemorrhage and white matter injury
- Mechanical ventilation
- Medical
- Nursing
- Persistent pulmonary hypertension
- Pneumothorax and air leak
- Respiratory
- Seizures
This paper is from 2020, more than five years ago. Newer evidence may have been published since.
Summary
This systematic review and meta-analysis evaluates mortality and complications of venovenous ECMO in newborns with severe respiratory failure refractory to maximal medical therapy. It pooled four observational studies including 347 neonates. It reports in-hospital mortality and the frequency of complications such as pneumothorax, cannula dysfunction, seizures, renal failure, infection, thrombosis and intracranial haemorrhage. The authors note the small, heterogeneous evidence base and call for larger, higher-quality trials.
Summary written for NICUlearn. Always read the original.
- Licence:
- Open (Creative Commons)
The full text of this openly licensed paper is available to NICUlearn members, and Neeky can answer questions from it.
Guidelines are shown for education. Follow your unit's own guidance and senior advice.