Evidence · Systematic review or meta-analysis
Benefits of probiotics in preterm neonates in low-income and medium-income countries: a systematic review of randomised controlled trials.
- Enteral feeding
- Infection
- Late-onset sepsis
- Medical
- Necrotising enterocolitis
- Nursing
- Nutrition and gastrointestinal
This paper is from 2017, more than five years ago. Newer evidence may have been published since.
Summary
Systematic review and meta-analysis of 23 randomised controlled trials (n=4783) from 10 low-income and middle-income countries comparing probiotics with placebo or no probiotic in preterm neonates. It assesses safety and efficacy for reducing mortality and morbidity, including necrotising enterocolitis and late-onset sepsis. Findings suggest probiotics have significant potential to reduce NEC, late-onset sepsis and mortality in preterm infants in resource-limited settings.
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- Licence:
- Open (Creative Commons)
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