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Evidence · Systematic review or meta-analysis

Long-term outcomes of survivors of neonatal insults: A systematic review and meta-analysis.

Systematic review or meta-analysisPLoS One2020Over 5 years oldFull text
  • Allied health
  • Congenital infections
  • Hypoxic-ischaemic encephalopathy and cooling
  • Infection
  • Jaundice and haematology
  • Jaundice and phototherapy
  • Medical
  • Neurodevelopmental follow-up
  • Neurology
  • Nursing

This paper is from 2020, more than five years ago. Newer evidence may have been published since.

Summary

This systematic review and meta-analysis examines long-term neurocognitive and mental health outcomes in survivors of neonatal insults followed to six years of age or older. It pooled 52 studies covering conditions including congenital rubella, congenital cytomegalovirus, hypoxic-ischaemic encephalopathy and neonatal jaundice. Neurodevelopmental impairment was the most commonly affected domain. The authors highlight limited long-term outcome data from sub-Saharan Africa despite the high burden of neonatal insults there.

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